Pharmacological evaluation of oral hypoglycemic and antidiabetic effects of fresh leaves ethanol extract of morinda lucida benth. in normal and alloxan- induced diabetic rats

A.A Adeneye, E.O Agbaje

Abstract


In the present study, 50 – 400 mg/kg of body weight/day of 50% ethanol
extract of the fresh leaves of Morinda lucida Benth. (MLE) was investigated
for its hypoglycemic and antidiabetic effects in adult normal and alloxaninduced diabetic male rats for 7 days. Acute oral toxicity study of MLE at the limit dose of 2000 mg/kg of body weight using Up-and-Down Procedure on statistical program, AOT425Pgm, was also conducted. Results showed that MLE significantly (p


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African Journal of Biomedical Research. ISSN: 1119-5096