Oral candidosis is one of the commonest oral manifestations of HIV  infection. The objective of this study was to determine the prevalence of oral candidosis in relation to CD4 counts and use of antiretroviral drugs among Nigerian HIV infected patients. Design: A cross-sectional study in which an interviewer administered questionnaire was used to collect data from 244 consecutive HIV patients aged 16-65years. They were examined for oral lesions including Oral candidosis. The presumptive criteria as defined by ECC Clearing House were used for diagnosis of oral lesions. Result: Forty-six (18.9%) patients presented with oral candidosis of various types. Pseudomembraneous candidosis was the commonest variant seen in 60.0% of those who presented with intra oral candidosis. Prevalence of oral candidosis was significantly associated with use of antiretroviral drugs (p