Heteropolyacides as green and reusable catalysts for the synthesis of [3,4-<i>b</i>][1,3,4] thiadiazines

Abstract

Synthesis of [3,4-b][1,3,4]thiadiazines from the condensation of 4-amino-6-methyl-3-thioxo-1,2,4-triazine-5(2H)-one (AMTTO) or 4-amino-1,4-dihydro-5-methyle-1,2,4-triazole-5-thione (AMTT) with phenacyl bromide in the presence of a catalytic amount of various heteropolyacids (HPAs) under refluxing conditions is reported.

KEY WORDS: Heteropolyacids, Phenacyl bromide, Heterocyclization, Thiadiazines

Bull. Chem. Soc. Ethiop. 2014, 28(1), 67-71.

DOI: http://dx.doi.org/10.4314/bcse.v28i1.8