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SIGMOISIDE E: A NEW ANTIBACTERIAL TRITERPENOID SAPONIN FROM ERYTHRINA SIGMOIDEA (HUA)

J. Kouam, X. Siewe Noundou, Laure B. Kouitcheu Mabeku, A. Meli Lannang, M. Iqbal Choudhary, Z.T. Fomum

Abstract


Chemical analysis of the stem bark of Erythrina sigmoidea (Leguminoseae) yielded two known isoflavones, 6,8-diprenylgenisteine (3) and warangalone (4) as well as a new triterpenoid saponin designated sigmoiside E (1). Its structure was established by chemical and spectroscopic means as 16-O-β-D-galactopyranosyl maniladiol (1). Sigmoiside E exhibited antibacterial activity against gram-negative bacteria.
KEY WORDS: Erythrina sigmoidea, Stem bark, Triterpenoid, Saponin, Isoflavone, Leguminoseae


Bull. Chem. Soc. Ethiop. 2007, 21(3), 373-378.



http://dx.doi.org/10.4314/bcse.v21i3.21218

Bulletin of the Chemical Society of Ethiopia.   ISSN: 1011-3924