The effect of the administration of 20mg/100g aqueous extract of the leaves of Tridax procumbens on the packed cell volume (PCV), daily weight gain, plasma lipid profiles and atherogenic indices of rats fed 1g/100g cholesterol, was investigated. The mean daily weight gain and plasma concentrations of triglyceride, LDL-, VLDL- and total cholesterol, as well as the atherogenic indices [Cardiac Risk Ratio (CRR), Atherogenic Coefficient (AC) and Atherogenic Index of Plasma (AIP)] of the treated animals were all significantly lower (p