Serum transaminases are highly diagnostic of hepatobiliary, cardiac, muscular, and other organ damages, while bicarbonates are useful index in assessment of pulmonary and respiratory problems. Reviews on the usefulness of these tools in evaluation of occupational health risks in quarry workers are hitherto limited. 57 and 22 workers of Abakaliki quarry industry and ministry of health respectively, who have worked for more than 10 years, were involved in the study. Alanine transaminases (ALT) and aspartate transaminase (AST) were analysed by enzymatic methods while measurement of bicarbonates (HCO3-) and chlorine (Cl-) was done by titrimetry. In males, AST, ALT, and HCO3- was significantly higher (P