Progressive pseudorheumatoid dysplasia misdiagnosed as seronegative juvenile idiopathic arthritis

Abstract

Background: Progressive pseudorheumatoid dysplasia (PPD) is a rare spondylo- epi-metaphyseal dysplasia (SEMD). It can be confused with juvenile idiopathic arthritis (JIA), both clinically and radiologically. Early detection and diagnosis of PPD are  important in helping to relieve the pain and disability associated with this disease and in avoiding unnecessary investigations and anti-rheumatic interventions.

Case Details: We report the case of a 15-year-old girl with PPD who was misdiagnosed with JIA.

Conclusion: In conclusion, PPD is a rare SEMD and can be confused with JIA, both clinically and radiologically. Early detection and diagnosis of PPD are important in helping to relieve the pain and disability associated with this disease and in avoiding unnecessary investigations and anti-rheumatic interventions.

Keywords: Progressive pseudorheumatoid dysplasia, juvenile idiopathic arthritis, spondylo-epi-metaphyseal dysplasia