A cross-sectional study was carried out to document the drug utilization pattern in 21 selected health facilities in Bahir Dar and west Gojam zones during a 12-month period using core and complementary drug use indicators developed by WHO/INRUD. A total of 808 patient record cards and 882 prescriptions were analyzed. The average number of drugs prescribed per encounter was 2.51 ± 0.5 with minimum and maximum values of 2 and 4, respectively. The percentage average antibiotic encounter was 50.7% ranging from 25 - 73.2% (p