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Beneficial effects of selected antioxdants in experimental diabetes
OC Ohaeri
Abstract
The antioxidant effects of Vitamins C, E and N-acetyl-L-cysteine (N) on glucose disposal, reduced glutathione (GSH), malonyldialdehyde (MDA) and antioxidant enzymes glutathione peroxidase (GPX) and glutathione reductase (GRT) in the levels of streptozotocin-induced diabetic rats was investigated.
Glucose tolerance test (GTT) levels of untreated rats (group 1) were relatively elevated in STZ rats compared with rats fed antioxidant, supplemented diets, (Vit. C + E, group 3) and (N+C+E, group 4), although both antioxidant supplemented and untreated rats did not dispose off any appreciable quantity of glucose. A significant level (P
Glucose tolerance test (GTT) levels of untreated rats (group 1) were relatively elevated in STZ rats compared with rats fed antioxidant, supplemented diets, (Vit. C + E, group 3) and (N+C+E, group 4), although both antioxidant supplemented and untreated rats did not dispose off any appreciable quantity of glucose. A significant level (P
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Global Journal of Pure and Applied Sciences. ISSN: 1118-0579