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Studies On The Effects Of An Alcohol Extract Of The Leaves Of Telfairia occidentialis On Alloxan Induced Diabetic Rats
A Olorunfemi Eseyin, C Arnold Igboasoiyi, Herbert Mbagwu, Ekaete Umoh, FJ Ekpe
Abstract
The effect of 96% ethanol extract of the leaf of Telfaria ocidentalis on alloxan induced diabetic rats were investigated. A dose of 500mg/kg of the extract was orally administered daily to the test animals for 9 days while the control animals received saline. The following biochemical parameters were evaluated: haemoglobin, glucose, cholesterol, total protein, proteins fractions, Alanine Amino transferase (ALAT) and Aspartate Transaminase (ASAT) levels. The weight of animal were also monitored. Glucose concentration and ASAT/ALAT quotient increased while ALAT activity decreased significally in the test animal compared with control (p
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Global Journal of Pure and Applied Sciences. ISSN: 1118-0579