OBJECTIVE: The aim of this study is to examine the pattern of total cholesterol, triglyceride, HDLcholesterol, and LDL-cholesterol in diabetic patients attending Jos university teaching hospital, Jos, in plateau central Nigeria. MATERIALS AND METHODS: Twenty-five diabetic subjects and 51 non diabetics were included in this study. Fasting plasma glucose and serum total Cholesterol, triglyceride, HDL – cholesterol were analyzed using standard procedures. The LDL-cholesterol was calculated using Friedewald’s formulae. RESULTS: Fasting plasma glucose and serum triglycerides were significantly Higher in diabetic subjects than control (p