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Published:
Nov 28, 2006Article Details
How to Cite
Wegwu, M., Ayalogu, E., & Sule, O. (2006). Anti-oxidant protective effects of <i> Cassia alata</i> in rats exposed to carbon tetrachloride. Journal of Applied Sciences and Environmental Management, 9(3), 77–80. https://doi.org/10.4314/jasem.v9i3.17356
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Anti-oxidant protective effects of Cassia alata in rats exposed to carbon tetrachloride
Abstract
The protective activity of Cassia alata against carbon tetrachloride (CCl4) – induced hepatotoxicity in rats was assessed. Crude extracts of petals of the plant in 0.5% ethanol were administered by intubation for 14 days prior to injection of 0.5ml Kg-1 CCl4 into the rats. Serum aspartate aminotransferase and alanine aminotransferase levels, 18 hours after CCl4 administration, decreased significantly (P < 0.05) in rats treated with the extracts than in CCl4 – treated rats only. These findings suggest that Cassia alata may be protective against hepatotoxin-induced liver damage in rats.
Journal of Applied Sciences and Environmental Management Vol. 9(3) 2005: 77-80
Journal of Applied Sciences and Environmental Management Vol. 9(3) 2005: 77-80
