Acetone extracts of the leaves of Anoigeissus leiocarpus collected from two different geographical locations from Nigeria were analysed for their phytochemicals, antioxidants, antibacterial, antimycoplasmal and cytotoxic activities. It was shown that plant from the colder region has higher yield and better activities than that from warmer region; having bacterial minimum inhibitory concentration (MIC) value of 0.08 mg/ml and mycoplasmal MIC value of 0.16mg/ml. The result showed that there were variations between the two plant extracts in their activities such as antimicrobial, phytochemicals, antioxidants and cytotoxicity.

Keywords: Anoigeissus leiocarpus; Antioxidant; Antibacterial; Antimycoplasmal; Cytotoxic