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Cassia occidentalis Caesalpiniceae haematology pathology and rats
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Muyibi, S., Olorode, B., Onyeyili, P., Osunkwo, U., Muhammad, B., & Ajagbonna, O. (2000). HAEMATOLOGICAL AND HISTOPATHOLOGICAL CHANGES OF CASSIA OCCIDENTALIS LEAF EXTRACT IN RATS. Nigerian Journal of Natural Products and Medicine, 4(1), 48–51. https://doi.org/10.4314/njnpm.v4i1.11748
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HAEMATOLOGICAL AND HISTOPATHOLOGICAL CHANGES OF CASSIA OCCIDENTALIS LEAF EXTRACT IN RATS
Abstract
The aqueous leave extract of Cassia occidentalis produced significant decreases in the packed cell volume (PCV), haemoglobin concentration (HB), and total red blood cell count (RBC) (P<0.05) but did not influence the white blood cell (WBC). Similarly the aqueous leaf extract produced histopathological lesions of the liver and kidney. These lesions include fatty changes and acute tubular necrosis in the liver and kidney, respectively. There was a dose dependent decrease weight changes in the rats given aqueous leaf extract of Cassia occidentalis. The results therefore indicate some level of toxicity in the use of this plant.
Key Words: Cassia occidentalis, Caesalpiniceae, haematology, pathology and rats
Nig. J. Nat Prod. And Med. Vol.4 2000: 48-51
Key Words: Cassia occidentalis, Caesalpiniceae, haematology, pathology and rats
Nig. J. Nat Prod. And Med. Vol.4 2000: 48-51
