Platelet Response To Methanolic And Aqueous Extracts Of Euphorbia hirta

E O Omeje, L Amayo, M U Adikwu, P O Osadebe, E Ibezim

Abstract




Euphorbia hirta Linn (Fam: Euphorbiaceae) locally known as ‘ogwu ugwo' (eczema drug) in some Eastern parts of Nigeria is used locally to arrest bleeding
in the event of an injury. The extracts (aqueous and methanolic) were administered orally to albino wistar rats. Platelet count, bleeding and clotting times were determined before and at different time intervals after administration of the extracts. The aqueous extract at 60 min reduced bleeding time by 54% compared to 49.5% for methanolic extract and was significant (P

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Nigerian Journal of Natural Products and Medicine.   ISSN: