A male infant with isolated prenatal hydrocephalus whose clinical features and family history were consistent with the diagnosis of X-linked hydrocephalus (Bickers-Adams syndrome) is described. Clinical, serological and radiological evidence for other causes of congenital hydrocephalus were lacking in the infant. Since the identification of an x-linked hydrocephalus has important consequences for genetic counselling, analysis of the family history of any male infant with isolated hydrocephalus is very important.

Nigerian Journal of Paediatrics 2001; 28:78. pp. 78-80