Summary: This study evaluated the action of aqueous leaf extract of Rothmannia longiflora on basal metabolic rate and electrolyte profile of alloxan-induced diabetic rats. Fifteen male Wistar (135 – 140g) were assigned to 3 groups of 5 rats each. Group 1 which served as control received placebo treatment; Group 2 - the diabetic (untreated) group also received placebo treatment whereas Group 3 – the extract treated diabetic group was administered the extract (15g/kg body weight) by oral administration for 14 days. Results of BMR measurement showed a significant increase (P