Leukocyte Profile in HIV Positive Adults in Owerri, Nigeria

Abstract

Leukocyte profile of 102 HIV positive asymptomatic adults (aged 18 – 56 years) in Owerri was compared with that of 80 HIV-negative adults (aged 22 – 50 years). The goal was to define early indicators of HIV-pathophysiology using leukocyte distribution pattern. Results show a definite pattern of leukopenia, relative lymphocyctosis and reduced blood level of CD4+ lymphocytes. Leukocyte profile may thus be an additional indication of HIV-infection but cannot replace HIV antibody tests for diagnostic purposes.

Key words: HIV infection, leukopenia, lymphocytosis, leukocyte profile

Nigerian Medical Practitioner Vol.47(4) 2005: 61-64