The effect of ethanol extracts of Chrysophyllum albidum fruit parts (namely pericarp, mesocarp, seed coat and seed cotyledon) on isolated rat uterus was investigated. The ethanol extracts of pericarp, mesocarp and seed coat were found to have no effect on the rat uterus as well as oxytocin-induced uterine contraction. When compared to isoproterenol, the extracts were observed not to have any uterine relaxant properties. However, the ethanol extract of the seed cotyledon exhibited minimal dose related uterine contraction and was also found to produce a partial increase on the oxytocin-induced uterine contraction. Phytochemical screening showed the presence of alkaloids, flavonoids, saponins, tannins and terpenoids.

Keywords:Chrysophyllum albidum, Uterine properties

Plant Product Research Journal Vol. 12 2008: pp. 4-5