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In the course of a continued investigation of the alkaloid constituents of the family Amaryllidaceae, 15 Amaryllidaceae alkaloids isolated from Crinum bulbispermum and C. moorei were tested for anti-inflammatory activity using cyclooxygenase assay (COX-1 and COX-2) and antibacterial activity against Bacillus subtilis, Staphylococus aureus, Escherichia coli and Klebsiella pneumoniae. The alkaloids showed only low inhibitory activity on COX-1 and COX-2. No bacterial growth inhibition was observed at the final concentration of 250µg ml^-1 used in this study.

South African Journal of Botany 2003, 69: 448–449