Main Article Content

Haematological alterations probably underlining anoestrus in synchronized <i>Trypanosoma brucei</i>-infected West African Dwarf (WAD) goats


O O Leigh
T O Ajibade
K O Soetan

Abstract

Haematological alterations are consistent with trypanosomosis, which is an important cause of reproductive wastage in many species of food animals.The haematological changes associated with Typanosoma brucei infection in oestrous synchronized goats were investigated using twelve adult West African Dwarf (WAD) does, randomly divided into two equal groups of six does each. The first group served as the control, and the second group was intravenously infected with rat-passaged T.brucei at a dose of 4.8 x 105trypanosomes. Both groups of does were synchronized with125 mcg chloprostenol sodium (Estrumate®) administered intramuscularly. Haematological analysis revealed significantly (P<0.05) lowered packed cell volume, haemoglobin concentration, red blood cell count, mean corpuscular volume, mean corpuscular haemoglobin, creatinine and bilirubin in the T.brucei infected does. Also, lymphocytosis, neutropaenia, and monocytopaenia were observed in the infected does. The study concluded that Trypanosoma brucei infection in synchronized does was associated with deleterious alterations in haematological and serum biochemical parameters, and that these may have underlining effects in the causation of anoestrus.

Keywords: Haematology, Biochemistry, Trypanosomosis, Anoestrus,WAD goat.


Journal Identifiers


eISSN: 0794-4845