A study was conducted in Turiani (sub-humid environment) and Mlali (semi-arid environment) to assess the seasonal variation of nematode infection in Small East African (SEA) goats and F₁ crosses of SAE with Saanen and Boer. The SEA goats were kept under extensive system while the crossbreds were kept under semi-intensive system. In Mlali 37 SEA goats and 30 SEA x Boer crosses while in Turiani 30 SEA goats and 33 SEA x Saanen crosses were included in the study. Worm burden was assessed using faecal egg count (FEC) and packed cell volume (PCV) as indicator traits. Faecal and blood samples were collected at the end of dry season, mid and end of rain season. The dominant worm species were identified by faecal culture. The results indicated that fewer animals (30 – 66.7%) were infected at the end of the dry season than at the mid and end of the rain season (69.7 – 100%). The FEC values differed significantly between periods of the year (P< 0.001) and between locations (P