Pattern of skin surface lipids in some South-Western Nigerians with acne vulgaris

CI Ikaraoha, GOL Taylor, JI Anetor, JA Onuegbu

Abstract


Unanswered questions still exist regarding pathophysiology of acne vulgaris generally and particularly in this environment.


Methods: Skin surface lipid (SSL) samples were collected by the heptane sponge technique from faces of 20 Nigerians with facial acne vulgaris and 25 controls. The subjects were classified into mild and moderately severe acne groups. Total cholesterol and triglycerides were determined and expressed in percentage (%) while Undetermined Skin Surface Lipids (USSL) (free fatty acids + squalene + wax ester +


diglycerides) were computed.


Results: Triglycerides and total cholesterol levels were significantly higher in subjects with acne vulgaris compared with controls (p < 0.001 and p

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West African Journal of Medicine.   ISSN: 0189-160X