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Annals of African Medicine

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Dyslipidemias in type 2 diabetes mellitus patients in Nnewi South-East Nigeria

NN Jisieike-Onuigbo, EI Unuigbe, CO Oguejiofor

Abstract


Background: Dyslipidemia has been noted to play an integral role in the pathogenesis and progression of micro and macrovascular complications in diabetes mellitus patients. The complications exemplified by renal   vascular and cardiovascular disease cause the most morbidity and mortality in this group of patients.
Objective: This study is aimed at understanding the pattern of  dyslipidemia among type 2 diabetic patients.
Materials and Methods: A total of 108 consenting adult type 2 diabetic  patients seen in the medical unit of the Nnamdi Azikiwe University Teaching Hospital Nnewi were evaluated in this crosssectional study. Their fasting lipid profile, fasting blood glucose, weight, height and blood pressure were evaluated.
Result: The prevalence of dyslipidemia (at least one abnormal lipid  profile) was 90.7%. The 24.1% had single dyslipidemia while 66.6% had combined dyslipidemia. Reduced HDL constituted the highest single  abnormality (62%) followed by hypertriglyceridemia (56.5%),  hypercholesterolemia (53.7%) and high LDL in (44.4%). The duration of DM was not significantly associated with dyslipidemia (P >0.05).
Conclusion: Dyslipidemia is highly prevalent among type 2 diabetic  patients in Nigeria with the majority of the patients having combined dyslipidemia. We recommend that aggressive treatment of lipidemia and hyperglycemia can be instituted to reduce the risk of macro and microvascular complications.



AJOL African Journals Online