Amyloid goitre following chronic osteomyelitis: case report and review of literature

Abstract

Amyloid Goitre is a rare clinical entity associated with systemic amyloidosis. It poses a significant diagnostic and therapeutic challenge and may be confused with a neoplastic goiter. We present the case of a 20 year old male patient who presented with a rapidly enlarging goiter, several years after resolution of chronic osteomyelitis. Histologic examination of the thyroidectomy specimen showed extracellular deposits of congophilic amyloid diagnostic of amyloid goitre. Similar cases in the literature are reviewed.

Keywords: amyloid goitre, thyroidectomy, osteomyelitis

Annals of African Medicine Vol. 4(4) 2005: 180–182