Ethylene Diamine Tetra-Acetic Acid (EDTA) Induced Pseudothrombocytopenia, (A Case Report.)

  • OE Ojeh-Oziegbe
  • TAT Salami
  • M Momoh


Thrombocytopenia caused by E.D.T.A can cause misdiagnosis of patients’ illness and may lead to inappropriate treatment if the problem is not recognized. We present this case of a male patient with spuriously low platelet count caused by EDTA. It is a phenomenon that results in low platelet count recorded by auto-analysers on blood collected in EDTA bottles. This phenomenon occurs as a result of anti-bodies that cause platelet aggregation in blood anti-coagulated with EDTA. These are anti-bodies in the IgM or IgG class reacting with the antigenic binding site of the gp II b glycoprotein.

Keywords: Pseudothrombocytopenia, EDTA, Ethylene Diamine tetra-acetic Acid


Journal Identifiers

eISSN: 1596-6569