Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda

  • Felix Bongomin
  • Richard Kwizera
  • Emmanuel Mande
  • Sharley Melissa Aloyo
  • Beatrice Achan
  • Martha Namusobya
  • Senai Goitom Sereke
  • Charles Batte
  • Sarah Kiguli
  • Joseph Baruch Baluku
  • Moses L Joloba
  • Bruce J Kirenga
Keywords: Invasive pulmonary aspergillosis; COVID-19; critical illness; Uganda.

Abstract

Invasive pulmonary aspergillosis is known to complicate the coronavirus diseases-2019 (COVID-19), especially those with critical
illness. We investigated the baseline anti-Aspergillus antibody serostatus of patients with moderate-critical COVID-19 hospitalized
at 3 COVID-19 Treatment Units in Uganda. All 46 tested patients, mean age 30, and 11% with underlying respiratory
disease had a negative serum anti-Aspergillus IgM/IgG antibody immunochromatographic test on day 3 (mean) of symptom
onset (range 1-26), but follow up specimens to assess seroconversion were not available.

Keywords: Invasive pulmonary aspergillosis; COVID-19; critical illness; Uganda.

Published
2022-10-28
Section
Articles

Journal Identifiers


eISSN: 1729-0503
print ISSN: 1680-6905