Cytotoxicity of chlopyrifos and cypermethrin: The ameliorative effects of antioxidants

Abstract

The present paper reviews the mechanism underlying chlorpyrifos and cypermethrin poisoning. It explains the mechanism of action of chlopyrifos and cypermethrin and the role of oxidative stress. It sheds light on the interaction between chlopyrifos and cypermethrin as observed in many cocktails of pesticide combinations today. It also explains the adverse health effects of pesticides and some antioxidants which may ameliorate their effects. Further research aimed at identifying more agents that may ameliorate chlorpyrifos and cypermethrin-induced toxicity should be carried out.

Key words: Pesticides, chlorpyrifos, cypermethrin oxidative stress, antioxidant.