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African Journal of Biotechnology

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Population genetic data for six non-combined DNA index system (non-CODIS) miniSTR loci from the Xhosa and Cape Muslim populations of South Africa

Zainonesa Abrahams, Mongi Benjeddou

Abstract


Allele frequency and forensic parameters for six non-combined DNA Index System (non-CODIS) miniSTR loci: D1S1627, D3S4529, D5S2500, D6S1017, D8S1115, and D9S2157 were calculated from a sample of 226  unrelated individuals from two populations (that is, Xhosa and Cape Muslim) of South Africa. No significant  deviation from Hardy-Weinberg equilibrium was found. All loci showed a moderate degree of polymorphism  with heterozygosity values >0.6 for both populations across all loci. The combined power of discrimination  was 0.999999675 and 0.999999037 for Xhosa and Cape Muslim populations, respectively. The respective  values for the combined power of exclusion in these populations were 0.94 and 0.99. The allele frequency data  generated can be used for estimating DNA profile frequencies for the studied populations residing in South  Africa.


Key words: Allele frequencies, MiniSTR, DNA typing, population data, South Africa.




http://dx.doi.org/10.5897/AJB11.2998
AJOL African Journals Online