Nano lab-on-chip systems for biomedical and environmental monitoring

  • Tijjani Adam
  • U Hashim
  • Th S Dhahi
  • Pei Ling Leow

Abstract

In recent years, nano lab-on-chip (NLOC) has emerged as a powerful tool for biosensing and an active area of research particularly in DNA genetic and genetic related investigations. Compared with conventional sensing techniques, distinctive advantages of using NLOC for biomedicine and other related area include ultra-high sensitivity, higher throughput, in-situ monitoring and lower cost. This review aims to summarize recent  advancements in two major types of NLOC sensing approaches, label and labelled free NLOC, as well as their biomedical applications. The state-of-the-art on how these sensors interface with nano/microfluidics is then presented and the latest papers in the area summarized and also proposal to develop compact NLOC with four different sensing elements with two different mechanisms, common and separate padding is prospected.

Keywords: Nano lab-on-chip, in-situ, nano/microfluidics, sensors, DNA

African Journal of Biotechnology Vol. 12(36), pp. 5486-5495

Author Biographies

Tijjani Adam
Institute of Nano Electronic Engineering (INEE), University Malaysia Perlis (UniMAP), 01000 Kangar Perlis Malaysia
U Hashim
Institute of Nano Electronic Engineering (INEE), University Malaysia Perlis (UniMAP), 01000 Kangar Perlis Malaysia
Th S Dhahi
Institute of Nano Electronic Engineering (INEE), University Malaysia Perlis (UniMAP), 01000 Kangar Perlis Malaysia
Pei Ling Leow
Faculty of (UTM), Johor Bahru, Malaysia.
Published
2016-05-11
Section
Articles

Journal Identifiers


eISSN: 1684-5315