In vitro evaluation of the interaction between tea extracts and penicillin G against staphylococcus aureus

  • CO Esimone
  • IR Iroha
  • EC Ibezim
  • CO Okeh
  • EM Okpana
Keywords: Penicillin G, tea extract, herb-drug interaction


The herb-drug interaction between tea (Carmelia sinensis) extract and penicillin G (Pen G) was investigated against three strains of Staphylococcus aureus using pair combinations in an in vitro decimal assay for additivity test. Results showed that the interactions between penicillin G and tea
extracts were mainly additive against the three strains of S. aureus. This suggests that the concomitant administration of tea and Pen G may not impair the antimicrobial activity of Pen G.

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eISSN: 1684-5315