Effect of Trimeresurus albolabris (green pit viper) venom on mean corpuscular volume, osmotic fragility and red blood cell morphology: A preliminary report

  • S Soogarun
  • M Chowbumroongkait
  • P Pradniwat
  • S Chanprasert
  • V Wiwanitkit
  • Y Suwanawong
  • T Moungkote
  • J Pawinwongchai
Keywords: Green Pit Viper, Mean Corpuscular Volume (MCV), Osmotic Fragility.

Abstract

An in vitro study was conducted by mixing small amounts of green pit viper venom with blood and observing changes. At a concentration of 10 mg crude venom, red blood cells (RBC) osmotic fragility slightly increased. RBC morphology changed to spherical shape which was compatible with what was observed in scanning electron microscope (SEM). However, there was no change in mean corpuscular volume (p > 0.05).
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eISSN: 1684-5315