African Journal of Biotechnology

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Fumaric acid, an antibacterial component of Aloe vera L.

CL He, BD Fu, HQ Shen, XL Jiang, XB Wei


The acetoacetate fraction partitioned from Aloe vera L. showed an effective antibacterial activity against four clinically frequent pathogenic bacteria. Through a series of chromatographic methods and activity assays, one compound was obtained and it has potent antibacterial activity. Based on the data of mass spectrometry, 1H-NMR, 13C-NMR and IR spectra, this compound was determined to be fumaric acid. This study concluded that fumaric acid is one of the antibacterial components in A. vera.

Key words: Fumaric acid, Aloe vera, antibacterial activity.
AJOL African Journals Online