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Thirst perception and dryness of mouth in healthy young adults nigerians


V.U Igbokwe
L Obika

Abstract

This study examined the threshold for thirst perception (TP) using the
visual analogue scale (VAS). Thirst perception (TP) and dryness of
mouth (DM) were studied in normal subjects, (n = 137; 78 males of
height, 1.72 ± 0.01, age, 23 ± 0.26, body mass index, 21.11 ± 0.29, and
59 females of height, 1.65 ± 0.01, age, 21 ± 0.23, body mass index,
21.0 ± 0.27). The results showed that (i) TP and DM in males, (1.21 ±
0.15 cm and 1.14 ± 0.16cm respectively) and in females, (1.10 ±
0.16cm and 1.04 ± 0.17cm respectively) were similar. (ii) The
relationship, Thirst (cm) = 0.75 (plasma arginine vasopressin ± 1.2)
exists and has a mean of not thirsty of 1.2cm at the lower end of the
scale. (iii) The plasma osmolality of 281mOsm/kg cannot be the
threshold for TP and the plasma osmolality of 285mOsm/kg or
284.3mOsm/kg cannot be the threshold for plasma arginine vasopressin
secretion but rather the mean of the lower set point of the scales for TP
and plasma arginine vasopressin [PAVP] secretion. (iv) The threshold for
TP using the VAS is between 1.50 - 1.575cm markings, and plasma
osmolality of 286.0 - 286.25 mOsm/kg. PAVP of 0.4 – 0.5 pmol/l
being the sensitivity of the osmoregulatory unit.
(Afr. J. Biomed. Res. 11: 39 - 46)


Key Words;
Thirst perception, Dryness of mouth, plasma osmolality, osmotic threshold, Visual Analogue Scale


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eISSN: 1119-5096
print ISSN: 1119-5096