THE EFFECT OF SCHISTOSOMA MANSONI CERCARIA INFECTION AND TREATMENT WITH NIRIDAZOLE ON TESTICULAR HISTOLOGY OF THE MICE.

Abstract

The testicular histology of mice infected with Schistosoma mansoni (S.mansoni) cercaria and treated with Niridazole was examined. The results reveal that infection of mice with Schistosoma mansoni cercariae resulted in distortion of the testicular cyto-architecture including disruption of spermatogenesis as shown by the absence of spermatozoa in the lumen of the sominiferous tubule and distruction of the inter-tubular connective tissue of the infected mice. These changes were reversed to normalcy following two-course treatment of the infected mice with Niridazole after five weeks.


(Af. J. of Clinical and Experimental Microbiology: 2003 4(1): 2-5)