Nosocomial infections: urinary tract infection in patients with indwelling urinary catheter

Abstract

With the aim of studying the pattern of urinary tract infection in patients with indwelling urinary catheter in the University College Hospital, Ibadan, a total of 164 patients were recruited. A questionnaire was administered to each pateint to provide information on demographic data, clinical diagnosis, and symptoms and signs suggestive of urinary tract infection. Catheter specimen urine from each of the patients was cultured to identify the agents of infection. Antimicrobial sensitvies of the isolates were done. It was found that 54. 8% of the patients were above 50 years of age, with a male to female ratio of 2: 1. Benign prostatic hyperplasia was the most common indication for catheterization.83. 5% and 16.5% had Intra-urethral and supra pubilc cathrterization respectively. 69. 5% of these patients had urinary tract infection with 90. 40%. 9.6% and 0.9% harbouring 1.2 and 3 organisms respectively. Intake of antibotics did not influence the incidence of urinary tract infection. The common agents of infection were klebsiella spp; Pseudomonas spp. Escherichia coli, Proteus spp. Staphylococcus aureus and candial albicans in order frequency. The bacterial agents of infection were resistant to ampicillin, cotrimoxazol and nitrofuradantion commonly used for the patient with urological problem. Ceftazidime, ceftrazone, pefloxacin and ofloxacin showed good sensitivity against the bacteria. These finding should be useful for those who manage patient with indwelling urinary catheter.


(Af. J. of Clinical and Experimental Microbiology: 2003 4(1): 63-71)