Article Sidebar
Article Details
Copyright: Creative Commons Attribution CC.
This license lets others distribute, remix, tweak, and build upon your work, even commercially, as long as they credit you for the original creation. This is the most accommodating of licenses offered. Recommended for maximum dissemination and use of licensed materials. View License Deed | View Legal Code Authors can also self-archive their manuscripts immediately and enable public access from their institution's repository. This is the version that has been accepted for publication and which typically includes author-incorporated changes suggested during submission, peer review and in editor-author communications.
Main Article Content
Astragaloside III from <i>Astragalus membranaceus</i> antagonizes breast cancer growth
Abstract
Background: Astragaloside III has been used to treat different cancers; however their effect on breast cancer remains unknown.
Materials and methods: The present study examined the effects of Astragaloside III from Astragalus membranaceus on breast cancer cell lines in vitro as well as xenograft in vivo.
Results: The results showed that the Astragaloside III could effectively reduce cancer cell survival in vitro and inhibit the tumor growth in vivo. The potential mechanism is the induction of cell apoptosis signaling pathways.
Conclusion: We believe that Astragaloside III provides a new therapeutic tool to treat breast cancer.
Keywords: breast cancer; Astragaloside III; apoptosis; treatment;
