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Published:
Oct 14, 2008Keywords:
<i>Mayodendron igneum</i> Bignoniaceae apigenin glycosides anti- inflammatory activity
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Phenolic Compounds And Bioactivity Of Leaves Of <i>Mayodendron igneum</i> Kurz
Abstract
Four apigenin glycosides were isolated from the ethyl acetate extract of the leaves of Mayodendron igneum Fam.Bignoniaceae. They were identified as apigenin 7-O-glucoside; 6-methoxy apigenin-7-O-glucoside; 6-methoxy apigenin-7-O-rhamnoglucoside and 6-hydroxy apigenin-7-O-rhamnoglucoside. In addition an isoflavone glycoside was isolated, and identified as genistin 5,4`-methyl ether. Ethanol (80%) extract of Mayodendron igneum leaves exhibited significant anti-inflammatory and analgesic activities. LD50 determination of the extract indicated the safety of the leaves of the plant.
Keywords: Mayodendron igneum, Bignoniaceae, apigenin glycosides, anti- inflammatory activity.
African Journal of Traditional and Complementary Medicine Vol. 4 (3) 2007: pp. 306-312
