Hypoglycaemic activity of the leaves extracts of Bersama engleriana in rats

  • Georgette Nyah Njike Animal Physiology and Phytopharmacology Laboratory, University of Dschang, PO BOX 67 Dschang, Cameroon
  • Pierre Watcho Animal Physiology and Phytopharmacology Laboratory, University of Dschang, PO BOX 67 Dschang, Cameroon
  • Télesphore Benoît Nguelefack Animal Physiology and Phytopharmacology Laboratory, University of Dschang, PO BOX 67 Dschang, Cameroon
  • Albert Kamanyi Animal Physiology and Phytopharmacology Laboratory, University of Dschang, PO BOX 67 Dschang, Cameroon
Keywords: Bersama engleriana, Hypoglycaemic effect, Leaf extract

Abstract

The hypoglycaemic properties of the aqueous and methanol extracts of the leaves of Bersama engleriana were evaluated in normoglycaemic rats in order to scientifically validate its traditional therapeutic use. With a dose of 300 mg/kg b.w. only the aqueous extract appeared to be significantly effective while at high dose, 600 mg/kg b.w., the aqueous and methanol extracts of Bersama engleriana reduced the blood glucose level by 37.7% and 49.11% after 8h of treatment of rats respectively. These results confirm the hypoglycaemic properties of some extracts of the leaves of Bersama engleriana with the aqueous extract appearing more active.
Key words: Bersama engleriana, hypoglycaemic effect, leaf extract
Afr. J. Trad. Comp. Alt. Med. Vol.2(3) 2005: 215 - 221
Published
2005-08-09

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eISSN: 0189-6016