African Journal of Traditional, Complementary and Alternative Medicines

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Study on anti-tumor effect of Solanum Lyratum thunb. Extract in S180 tumor-bearing mice

Y Guan, H Zhao, X Yan, J Meng, W Wang


The objective of the study was to investigate the anti-tumour effect of ethanol extract of Solanum lyratum Thunb. in S180 tumour-bearing mice, and to preliminarily explore its mechanism of action. Methods: Mice were made into S180Solanum lyratum Thunb. extract had certain tumour inhibitory effect, which can elevate the serum IL-2, TNF-a contents, and increase the thymus and spleen indices to a certain extent. The study concluded that Solanum lyratum Thunb. extract has certain in vivo anti-tumour effect which may be exerted through enhancing the body immunity.

Key words: Solanum lyratum Thunb.; S180 sarcoma; tumour inhibition rate

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