https://www.ajol.info/index.php/ampdr <p><strong>Medical and Clinical Research</strong></p> <p>This section publishes a wide range of clinical studies and reports that contribute to the advancement of medical research and clinical practice for physicians, as well as hospital pharmacy, pharmacy practice and biostatistics.</p> <p>Medical and Clinical Research section covers all fields of medical and clinical practice including but not limited to: Anesthesiology and pain management, Cardiovascular disorders, , Critical care and emergency medicine, Research on different advance surgery, Dermatology, Endocrinology, Epidemiology, Gastroenterology and hepatology, Genetics and genomics, Geriatrics, Hematology, , Infectious diseases, Nephrology, Neurological disorders, Psychoneurological research and reports, Neuroscience, Nutrition, Obstetrics, Gynecology, Oncology, Ophthalmology, Otolaryngology, Pathology, Pediatrics and child health, Physiology, Public health and epidemiology, Radiology and medical imaging, Rheumatology, Surgery, Urology, and biostatisctics for clinical studies.</p> <p><strong>Advanced Research in Pharmaceutical Sciences</strong></p> <p>This section welcomes manuscripts covering a wide range of aspects involved in pharmaceutical sciences. The following topics are considered: Pharmaceutics, Novel drug delivery systems, Nanotechnology, Pharmacy practice, Pharmacognosy, Natural products chemistry and analysis, Metabolomics, Pharmaceutical medicinal chemistry, Computer aided drug design, Drug discovery, Molecular modelling, Insilco docking, Bioinformatics, Pharmaceutical Analytical Chemistry, Organic Chemistry and Pharmaceutical Biotechnology.</p> <p>This section also publishes original research findings and review articles related to cellular biology, Biochemistry, Tissue/organ and whole animal pharmacology, Drug interactions and toxicology, Genetics, Microbiology, Immunology, Biostatistics, Computational biology, Microbiology, Pharmaceutical Biotechnology and Pharmacogenomics are also included within the scope of this section.</p> <p>Special interest is considered to computer aided drug design (CAAD) drug discovery, computational chemistry, Structure activity relationship, molecular modeling, and bioinformatics, as well as natural products Natural products chemistry including plants, marines and fungi; natural products analytical studies and pharmacokinetic investigations; molecular biology, genetics, structure and bioactivities of phytochemicals, including '-omics' and bioinformatics/computational biology; formulation and drug delivery of natural products in addition to food chemistry, food biochemistry and analytical approaches.</p> <p><strong>Experimental and Applied Dental research</strong></p> <p>In the section of experimental and applied dental research, the journal focuses on highlighting the novel concepts in dental treatment and education ranging from contemporary approaches to modern era of digital and regenerative Dentistry.</p> <p>The journal aims at providing a platform for researchers in all fields of dentistry where they can publish both basic science and clinical researches serving all dental fields and practices.</p> <p>The journal accepts all article types ranging from in-vitro, clinical studies and all types of reviews. The journal also encourages the publication of multidisciplinary researches spanning pharmaceutical, medical, biomedical engineering, biotechnology and artificial intelligence fields.</p> <p>The target authors include researchers, clinicians, graduate students and dental educators.</p> <p>This journal's own website can be viewed <a href="http://apc.aast.edu/ojs/index.php/AMPDR/index" target="_blank" rel="noopener">here</a>.</p> Academy Publishing Center (APC), Arab Academy for Science, Technology and Maritime Transport (AASTMT) en-US Advances in Medical, Pharmaceutical and Dental Research 2812-488X <p>AMPDR journal provides immediate open access to all content on the principle that making research freely available to the public supports a greater global exchange of knowledge. AMPDR grants usage rights to others using the open license CC-BY-NC allowing for immediate free access to the work and permitting any user to read, download, copy, distribute, print, search, or link to the full texts of articles, crawl them for indexing, pass them as data to software, or use them for any other lawful purpose.</p> <p> </p> https://www.ajol.info/index.php/ampdr/article/view/259631 <p><strong>Introduction</strong>: Over 2 billion people worldwide, and 14.6% of India’s population consumes alcohol, 18.5% of whom are&nbsp; dependent. 95% of alcohol users are males, with 74% falling in the age bracket of 18-49 years. Stressful life events and&nbsp; personality may act as important determinants in persistence of alcohol use, hence influencing long term treatment of&nbsp; alcohol dependent individuals. This study focuses on these aspects to fill in the dearth of research on this concept over&nbsp; the past decade.</p> <p><strong>Methodology</strong>: A case control study was done at a tertiary care hospital with 80 literate male participants; 40 cases&nbsp; meeting the criteria for alcohol dependence as per ICD 10, and 40 age matched controls with no history of alcohol&nbsp; consumption. Participants were screened with General Health Questionnaire-12 to exclude other illnesses. All&nbsp; participants were administered sociodemographic proformas, Presumptive Stressful Life Events Scale, Eysenck&nbsp; Personality Questionnaire - Revised.</p> <p><strong>Results</strong>: Sociodemographic profiles of cases and controls were similar. Mean&nbsp; number of life events and undesirable life events were higher among cases, and mean number of desirable life events&nbsp; were higher among controls. Cases displayed higher scores in the domains of psychoticism, neuroticism and&nbsp; extraversion.</p> <p><strong>Conclusion</strong>: Alcohol dependent individuals differ significantly from life time abstinent individuals on personality variables and had experienced more subjective distress. A holistic approach addressing coping strategies,&nbsp; personality development, and education about substance use among adolescents would aid in individual and social well&nbsp; being.</p> Preeti Gudlavallety Sumaiya Saleem Ahmed Pragathi Gollepally Copyright (c) 2023 https://creativecommons.org/licenses/by-nc/4.0 2023-11-21 2023-11-21 3 1 1 7 https://www.ajol.info/index.php/ampdr/article/view/259634 <p><strong>Background</strong>: Dilaceration is a rare dental condition that can occur during tooth development, resulting in distortion of&nbsp; the normal axial relationship between the crown and root. Although it can affect any tooth, it most commonly occurs in&nbsp; permanent incisors, often as a result of trauma to the primary predecessor. The impact of even a slight displacement of&nbsp; a primary incisor can be significant, disrupting the normal development of the follicles of new permanent teeth. Despite&nbsp; its rarity, dilaceration can pose significant challenges for dental professionals in terms of diagnosis and treatment. Case</p> <p><strong>Description</strong>: A case report of a 27-year-old female patient is presented, who attended with a missing maxillary left permanent central incisor and a hard palpable bulge in the maxillary vestibular area. Radiography revealed an impacted&nbsp; maxillary left central incisor, which was found to be dilacerated with a 120⁰ angle. Consequently, surgical&nbsp; extraction of the impacted tooth was planned as orthodontic extrusion is not a viable option in such cases. The extracted&nbsp; tooth was found to have no signs of resorption, and healing was progressing satisfactorily.</p> <p><strong>Conclusion</strong>:&nbsp; Radiography is the most reliable method of detecting the condition. The report emphasizes the importance of detecting&nbsp; dilaceration early and adhering to basic principles for its diagnosis and management.</p> <p><strong>Clinical Significance</strong>: The report&nbsp; provides valuable insights for dental professionals on the surgical management of severely dilacerated teeth and the&nbsp; need for a multidisciplinary approach due to the high risk of root fractures.</p> Shahab Javanmardi Abubaker Qutieshat Copyright (c) 2023 https://creativecommons.org/licenses/by-nc/4.0 2023-11-21 2023-11-21 3 1 8 11