⁶⁸Gallium‑DOTANOC positron emission tomography/computed tomography scintigraphy for an unusual case of malignant pheochromocytoma: Findings and review of literature

Abstract

Functional imaging is an important step in the diagnostic approach of patients with pheochromocytoma (PCC). Metaiodobenzylguanidine (MIBG) scintigraphy (single‑photon emission computed tomography) is currently the most widely used functional imaging modality for evaluating a case of PCC. However, it has some limitations and poor sensitivity, especially in cases of malignant PCC (MPCC). Positron emission tomography (PET) scanning with gallium‑68 (⁶⁸Ga)‑DOTA‑coupled somatostatin analogs is the newer upcoming modality with some superiority over MIBG scan. We present a case of MPCC with unusual invasion and metastasis positive on DOTANOC PET scan along with relevant review of literature.

Keywords: ⁶⁸Gallium‑DOTANOC positron emission tomography scan, malignant pheochromocytoma, metaiodobenzylguanidine scan