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Background/Purpose: Conjoined twins are rare and complex anomalies of the newborn. It is reported in 1/50.000 to 1/100.000 live births. The aim of the study was to summarize the experiences gained during separation of 5 sets of conjoined twins with presentation of literature review. Materials & Methods: During the period from January 2003 to June 2009, 5 sets of Conjoined twins had been separated during the first month of life. Two sets were symmetrical while the other 3 sets were asymmetrical. Results: Urgent separation of 3 sets of conjoined twins had been performed due to respiratory embarrassment. Elective surgery was performed for the case presented as fetus in fetu and the case of thoraco- omphalopagus twins in which the shared liver was divided between both babies. The short term postoperative follow up revealed uneventful course of 6 children resulting from separation of 5 sets of conjoined twins. Conclusion: Parasitic twins and twins with sever anomalies incompatible with life in one of them are considered to be one person. Timing of separation and separation plan should be individualized according to the need of urgent separation and the degree of organ fusion.
Index Word: conjoined twins, management, neonatal period.