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Animal Research International

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Production Of Some Virulence Factors Under Different Growth Conditions And Antibiotic Susceptibility Pattern Of Aeromonas hydrophila

U E Dibua, G Okpokwasili

Abstract




The production of some virulence factors under different growth conditions and antibiotic susceptbility pattern of Aeromonas hydrophila were investigated in this sudy. The virulence actors tested on the isolates included haemolytic activity, exopolysaccharide (capsule) and toxin production. Other cell property evaluated was antibiotic resistance. Of the several chemotherapeutants tested, streptomycin had Minimal Inhibitory Concentration (MIC) and Minimal Cidal Concentration (MCC) at 25 μg/ml; flumequine, MIC 15 μg/ml and MCC 20 μg/ml; nitrofurantoin, MIC 20 μg/ml and MCC at 20 μg/ml; chloramphenicol, MIC 15 μg/ml and MCC 30 μg/ml and nalidixic acid, MIC 25 μg/ml, MCC 30 μg/ml, respectively. Virulence characteristics wereapparent from the study; the properties exhibited such as ß-haemolytic activity (F= 1.32551; p < 0.001) and toxin producton (F = 0.141; p > 0.05) were evidence of the pathogenic potential of A. hydrophila.

Keywords: Virulence, Haemolytic activity, Susceptibility, Antibiotics, Aeromonas hydrophila

Animal Research International Vol. 3 (2) 2006 pp. 439-447



http://dx.doi.org/10.4314/ari.v3i2.40767
AJOL African Journals Online