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Haematological parameters of blood donors with erythrocytosis

S Kamaruzzaman, N Noor, W Abdullah, M Ramli, E Jamian, M Hasan, M Othman

Abstract


Background: It is mandatory for all blood donors to have their haemoglobin values tested before blood donation. High haemoglobin levels may indicate an underlying hidden pathological condition.

Aim: Our aim was to assess the frequency of erythrocytosis in blood donors and its correlation with other haematological parameters.

Methodology: All blood donors found to have high pre-donation haemoglobin levels during a nine-month period were included. Full blood counts and peripheral blood films were performed in addition to pre-donation screening, and all data were analysed using SPSS software version 23.0.

Results: The prevalence of blood donors with erythrocytosis was 7.8% (n=175). The range of haemoglobin for blood donors with erythrocytosis was between 13.9 and 19.1 g/dL (mean 16.0 g/dL). The highest haemoglobin level recorded for male and female  donors was 19.1 g/dL and 16.2 g/dL respectively. Positive correlation was noted between the number of donations and haemoglobin among blood donors.

Conclusion: There were significant variations in the haematological parameters in blood donors with erythrocytosis. Erythrocytosis in blood donors may indicate an underlying disease state. Donors identified with erythrocytosis should be referred for appropriate investigations.

Keywords: Blood donor, erythrocytosis, haematological parameters




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