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Functional Outcome After Surgical Excision of Cortical Meningio-Angiomatosis
Abstract
Objective: To study the functional outcome after surgical excision of cortical meningio-angiomatosis (MA) in terms of seizure control and neurological disability.
Methods: Four patients with MA were diagnosed with refractory epilepsy. All were surgically treated.
Results: Four cases of MA were reported three males and one female. Median age at presentation was 19 years (range 9–23 years). All patients had refractory seizures for 1–18 years with a median of 8 years. Two patients had exclusively simple partial seizures, with secondary generalization; the other two patients had complex partial seizures, with secondary generalization. CT and MRI were done for all patients. The lesion was in the right frontal lobe in one patient, left frontal in one patient, left tempropolar in one patient and right temporal in one patient.
After surgical resection, three patients remained seizure free without antiepileptic treatment and the fourth patient became controlled on monotherapy of antiepileptic treatment. No patients had added neurological deficit in the postoperative follow-up period of six months to eight years (mean 4.7 years)
Conclusion: MA commonly presents as refractory epilepsy. Although MA occurs infrequently, it is important to establish the correct diagnosis. Surgical excision is usually associated with good functional outcome with the patients either stop the antiepileptic treatment or become controlled on smaller doses.
Key words: Epilepsy, meningio-angiomatosis, surgery.
Methods: Four patients with MA were diagnosed with refractory epilepsy. All were surgically treated.
Results: Four cases of MA were reported three males and one female. Median age at presentation was 19 years (range 9–23 years). All patients had refractory seizures for 1–18 years with a median of 8 years. Two patients had exclusively simple partial seizures, with secondary generalization; the other two patients had complex partial seizures, with secondary generalization. CT and MRI were done for all patients. The lesion was in the right frontal lobe in one patient, left frontal in one patient, left tempropolar in one patient and right temporal in one patient.
After surgical resection, three patients remained seizure free without antiepileptic treatment and the fourth patient became controlled on monotherapy of antiepileptic treatment. No patients had added neurological deficit in the postoperative follow-up period of six months to eight years (mean 4.7 years)
Conclusion: MA commonly presents as refractory epilepsy. Although MA occurs infrequently, it is important to establish the correct diagnosis. Surgical excision is usually associated with good functional outcome with the patients either stop the antiepileptic treatment or become controlled on smaller doses.
Key words: Epilepsy, meningio-angiomatosis, surgery.
