GC-MS and HPLC analysis of crude extracts of stem bark of <i>Adansonia digitata</i>

Abstract

The present investigation was carried out to characterize the chemical profile of the crude extract of stem bark of Adansonia digitata using GC-MS and HPLC analysis The plant stem bark were extracted using three solvents, the crude extracts of each solvent were characterized using Gas chromatography mass spectrometry (GC MS) analysis \High performance liquid chromatography (HPLC) analysis. GC-MS analysis revealed the chemical profile of the extract with different compound, distinct peak, retention time (RT), molecular formular, molecular weight (MW), and chemical structure and area%. With fifteen (15) components identified in pet. Ether, twenty two (22) components were identified in ethanol and Eight (8) components were identified in aqueous extracts. The HPLC analysis shows different compounds with distinct peaks and their retention times. The presence of various compounds confirms the use of stem bark extract of Adansonia digitata for the treatment of various ailments by traditional system of medicine.

Keywords: Adansonia digitata, Gc-Ms analysis, HPLC analysis, Stem bark and extract.