ANTIPARASITIC PRENYLATED ISOFLAVONOIDS FROM SEEDS OF MILLETTIA GRIFFONIANA

Dieudonne Ngamga<sup>a</sup>; Emmanuel Yankep<sup>b</sup>; Pierre Tane<sup>a</sup>; Merhatibeb Bezabih<sup>c</sup>; Bonaventure T. Ngadjui<sup>b</sup>; Z. Tanee Fomum<sup>b</sup>; Berhanu M. Abegaz<sup>c</sup>*

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Published:

Jul 20, 2005

DOI:

Keywords:

Millettia griffoniana Fabaceae Papilionoideae Isoflavones Trypanocidal Anti-plasmodial

Issue

Vol. 19 No. 1 (2005)

Section

Articles

Dieudonne Ngamgaa

aDepartment of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon

Emmanuel Yankepb

bDepartment of Organic Chemistry, Faculty of Science, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon

Pierre Tanea

aDepartment of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon

Merhatibeb Bezabihc

cDepartment of Chemistry, Faculty of Science, University of Botswana, P.O. Box UB00704, Gaborone, Botswana

Bonaventure T. Ngadjuib

bDepartment of Organic Chemistry, Faculty of Science, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon

Z. Tanee Fomumb

bDepartment of Organic Chemistry, Faculty of Science, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon

Berhanu M. Abegazc*

cDepartment of Chemistry, Faculty of Science, University of Botswana, P.O. Box UB00704, Gaborone, Botswana

Abstract

Two new prenylated isoflavonoids, namely 7-methoxyebenosin and griffonianone E along with the known calopogonium isoflavone B and 7,2\'-dimethoxy-4\',5\'-methylenedioxy isoflavone were isolated from the seeds of Millettia griffoniana. Their structures were assigned on the basis of spectroscopic data. The new compounds exhibit moderate trypanocidal and anti-plasmodial activities.

KEY WORDS: Millettia griffoniana, Fabaceae, Papilionoideae, Isoflavones, Trypanocidal, Anti-plasmodial

Bull. Chem. Soc. Ethiop. 2005, 19(1), 75-80.

Bulletin of the Chemical Society of Ethiopia
Journal / Bulletin of the Chemical Society of Ethiopia / Vol. 19 No. 1 (2005) / Articles

Published:

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<b>ANTIPARASITIC PRENYLATED ISOFLAVONOIDS FROM SEEDS OF <i>MILLETTIA GRIFFONIANA</i></b>

Dieudonne Ngamga<sup>a</sup>

Emmanuel Yankep<sup>b</sup>

Pierre Tane<sup>a</sup>

Merhatibeb Bezabih<sup>c</sup>

Bonaventure T. Ngadjui<sup>b</sup>

Z. Tanee Fomum<sup>b</sup>

Berhanu M. Abegaz<sup>c</sup>*

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Dieudonne Ngamga<sup>a</sup>

Emmanuel Yankep<sup>b</sup>

Pierre Tane<sup>a</sup>

Merhatibeb Bezabih<sup>c</sup>

Bonaventure T. Ngadjui<sup>b</sup>

Z. Tanee Fomum<sup>b</sup>

Berhanu M. Abegaz<sup>c</sup>*

Abstract

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