Metal complexes of salicylhydroxamic acid and 1,10-phen-anthroline; equilibrium and antimicrobial activity studies

  • A. E. Fazary
Keywords: Salicylhydroxamic acid, 1, 10-Phenanthroline, Potentiometry, Antifungal and antibacterial activities


Salicylhydroxamic acid and its binary and ternary copper(II), nickel(II), and iron(III) complexes involving 1,10-phenanthroline were studied pH-potentiometrically in 0.15 mol.L-1 NaNO3 aqueous solutions at 37 oC. The protonation constants of salicylhydroxamic acid and 1,10-phenanthroline as well their binary and mixed ligand complex species stability constants were determined based on 3 estimation models (Irving Rossetti, Bjerrum-Calvin and Hyperquad 2008). Also, six solid complexes were synthesized and their biological activities were evaluated against some pathogenic bacteria and fungi organisms.


KEY WORDS: Salicylhydroxamic acid, 1,10-Phenanthroline, Potentiometry, Antifungal and antibacterial activities


Bull. Chem. Soc. Ethiop. 2014, 28(3), 393-402.



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eISSN: 1726-801X
print ISSN: 1011-3924