Synthesis and antioxidant activity of novel 8-formyl-4-substitued coumarins

  • H. Ç. Onar
  • B. A.Vardar
Keywords: Coumarin, Antioxidant activity, DPPH method

Abstract

4-Methyl-8-formyl- and 4-phenyl-8-formyl coumarins have been synthesized by Pechmann reaction using oxalic acid catalyst for the first time. 4-Propyl-7-hydroxy-, and 4-methyl-7-methoxy coumarins have also been accomplished by this catalyst for the first time. They have been characterizated by IR, 1H-NMR, 13C-NMR, mass and elemental analysis. Furthermore, the obtained coumarins were compared according to antioxidant activity by DPPH method.

               

KEY WORDS: Coumarin, Antioxidant activity, DPPH method

 

Bull. Chem. Soc. Ethiop. 2018, 32(1), 175-178

DOI: https://dx.doi.org/10.4314/bcse.v32i1.17

Published
2018-04-12
Section
Articles

Journal Identifiers


eISSN: 1726-801X
print ISSN: 1011-3924